![]() In addition, the nystatin group had a higher proportion of patients using disconnecting twin-bag exchange systems and had a significantly lower peritonitis rate compared with the control. The two groups were of similar age but the nystatin group had a significantly higher percentage of diabetics. Occurrence of FP and antibiotic-related FP (AR-FP) in patients with and without nystatin prophylaxis was compared. Nystatin tablets (500,000 units, 4 times per day) were given orally during whatever use of antibiotics to cover the whole course of antibiotic therapy. The control group included 320 patients (total follow-up 8875 patient-months) being treated without nystatin before October 1999 the nystatin group included 481 patients (total follow-up 13725 patient-months) being treated after October 1999. Incident and prevalent patients receiving CAPD between April 1995 and April 2005 at our center were included and divided into 2 groups. The aim of the present study was to evaluate the effect of nystatin prophylaxis on the occurrence of FP in programs with a relatively modest baseline FP rate. The role of nystatin prophylaxis during antibiotic therapy in the prevention of FP remains controversial, especially in programs with a modest or low baseline FP rate. Medications such as phenytoin and rifampicin can decrease the blood level of itraconazole and ketoconazole, making them less effective.Fungal peritonitis (FP) is a serious complication of continuous ambulatory peritoneal dialysis (CAPD), being associated with significant morbidity and mortality.There is a risk of muscle weakness if combined with cholesterol lowering drugs such as simvastatin or atorvastatin.The blood concentration of digoxin, midazolam and cyclosporine may be increased when taken with itraconazole or ketoconazole.There are potential interactions between itraconazole or ketoconazole with other medications.You are taking any other medications, including supplements, traditional medications and herbal remedies.Effective contraception is recommended for any woman who is taking itraconazole or ketoconazole who could potentially become pregnant during treatment and for 2 months following the end of treatment.You are pregnant, planning to become pregnant, or breastfeeding.You are allergic to this medication or any of the other ingredients of this medication.If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately. Burning, numbness, or abnormal tingling feeling.Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable. Increased sensitivity to sunlight, and severe burning may result.It is recommended that you avoid planning for a child with your partner during treatment with griseofulvin and for 6 months following therapy. Griseofulvin may affect sperm quality and production.Use a different or additional non-hormonal means of birth control while you are taking griseofulvin and for one month after stopping griseofulvin.​Reduced effectiveness of oral contraceptives and higher risk of unwanted pregnancy.If any of these side effects do not go away or are serious, please see your doctor. Complete the course as prescribed by the doctor.Keep the suspension in the mouth for as long as possible and swallow the medication. Swish the suspension around in your mouth.Use a dose-measuring dropper to measure the specified dose of the suspension.Shake the suspension well before measuring a dose.You may take this medication with or without food.Terbinafine and Fluconazole may be taken with or without food.Griseofulvin, Itraconazole and Ketoconazole should be taken with or after food.Do not stop taking your medication without checking with your healthcare professional.Common side effects of these medications include:
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